Hello, AncestryDNA.txt!

This individual's Ydna is : --> F --> G --> G2 --> G2a

Gender Score is 1.000

AncestryDNA.txtis 100.000% Likely to be Male

AncestryDNA.txtis 0.000% Likely to be Female

0 A variants out of 0 Total

0 B variants out of 0 Total

0 C variants out of 8 Total

0 D variants out of 0 Total

0 E variants out of 68 Total

0 E1b variants out of 2 Total

0 E3b variants out of 2 Total

93 F variants out of 93 Total

42 G variants out of 43 Total

0 G1 variants out of 3 Total

7 G2 variants out of 7 Total

2 G2a variants out of 2 Total

0 G2b variants out of 2 Total

0 H variants out of 0 Total

0 H1 variants out of 0 Total

0 H2 variants out of 1 Total

0 IJ variants out of 22 Total

0 I variants out of 25 Total

1 I1 variants out of 40 Total

0 I1a variants out of 0 Total

0 I1b variants out of 0 Total

0 I2 variants out of 3 Total

0 I2a variants out of 0 Total

0 I2b variants out of 2 Total

0 J variants out of 11 Total

0 J1 variants out of 3 Total

0 J1a variants out of 2 Total

0 J1b variants out of 0 Total

0 J2 variants out of 7 Total

0 J2a variants out of 4 Total

0 J2b variants out of 3 Total

0 K variants out of 2Total

0 L variants out of 10Total

0 T variants out of 8Total

0 T1 variants out of 1Total

0 T2 variants out of 0Total

0 N variants out of 9Total

0 O variants out of 4Total

0 Q variants out of 5Total

0 Q1 variants out of 4Total

0 Q2 variants out of 2Total

0 R variants out of 62Total

1 R1a variants out of 12Total

0 R1b variants out of 15Total

0 R2 variants out of 10Total

Results Mental Health

"Warrior" Phenotype - Quick dopamine reuptake, low dopamine levels, high stress resilience 16.667 %.

"Intermediate" Phenotype, intermediate dopamine levels and ability to tolerate stress 42.857 %.

"Worrier" Phenotype, slower dopamine reuptake and higher dopamine levels, lower stress resilience 40.476 %.

AG in COMT's Val/Met variation, meaning Val/Met , intermediate speed of dopamine reuptake, and intermediate dopamine levels.

CT in rs4633, intermediate levels of the COMT protein and protection from endometrial cancer, intermediate pain sensitivity

CT in COMT's rs4646312, slightly higher odds of schizophrenia (Odds ratio 1.25 per risk allele, pval 8 x 10-6). Risk allele is C

GG in COMT's rs6267, which is the typical for most humans and leads to slightly lower risk of Schizophrenia

AA in COMT's rs165599 variation, which leads to a decreased risk of Schizophrenia and Bipolar disorder.

GG in rs3027452,higher level of MAOB enzyme - typical genotype. Tryptophan more effective for depression.

CC in MAOB's rs1799836; Lower odds of ADHD, Parkinson's, One study found higher odds of Schizophrenia

GG in MAOB's rs6324, typical (lower) ADHD risk, most common genotype

TT in MAOA's rs6323, leading to lower activity of the MAOA enzyme and slower breakdown of dopamine, thus higher dopamine levels and certain advantages in attention tasks.

AA in MAOA's rs1800659, lower odds of post-surgical pain.

GG in MAOA's rs979605, decreased MAOA activity, worrier .

TT in MAOA's rs766117, lower risk of depression

Less D2 dopamine receptors 10.169 %.

Intermediate number of D2 dopamine receptors 42.373 %.

Higher number of D2 dopamine receptors 47.458 %.

GG, which means no derived No-Go Learner variants in DRD2's Pro319Pro variation, which means a higher number of D2 receptor sites in the brain, and a higher likelihood of schizophrenia

AA in DRD2's rs6275 variation, meaning increased number of dopamine D2 receptors and a higher risk of Schizophrenia.

CC in DRD2's rs2514218, higher odds of Schizophrenia

AG genotype in rs4648317 of DRD2, which is implicated in a slightly increased number of Dopamine D2 receptor sites in the brain and a slightly increased likelihood of Schizophrenia.

GG in Taq1 variation of DRD2, which is the typical for most humans leading to a slightly higher number of D2 dopamine receptors, and to a slightly lower risk of ADHD and Alcoholism.

CT in DRD2's rs12363125, one allele for higher odds of cocaine abuse and migraine risk

AA in DRD2's rs6589377, higher (typical) odds of neuroticism, but lower odds for nicotine dependence.

CC in rs5326 of DRD1, which is the typical for most humans and leads to a slightly lower risk of various mental health conditions.

AA in rs686 of Dopamine Receptor D1 gene, which leads to a higher likelyhood of Autism.

TT in rs4532 of DRD1, a typical associated with slightly higher odds of Autism and tobacco addiction.

GG in rs265981 of DRD1, which is the typical for most humans, and leads to a slightly higher risk of Schizophrenia and nicotine dependence.

GG in DRD1's rs265974, ~1.29x odds of substance use disorders.

GG in DRD1's rs265976, Patients with schizophrenia may have a better response when treated with clozapine as compared to patients with the GT genotype. Other genetic and clinical factors may also influence response to clozapine.

TT in rs6280 of DRD3, a typical associated with a slightly lower risk of OCD and intellectual disability.

AA in DRD3's rs167771 variation, mostly a Eurasian genotype , increases the risks of autism and autistic personality traits such as rigid behavior.

AG in DRD3's rs963468, higher odds of schizophrenia, risk allele is A (doesn't play a role in the polygenic risk score calculation).

No risk variants for mental retardation in DRD4's rs752306 (CC)

CC in DRD5's rs6283. Higher odds of ADHD; mechanism of action is not exactly known

Lower levels of 5-HT (Serotonin) 30.769 %.

Intermediate levels of 5-HT (Serotonin) 57.692 %.

Higher levels of 5-HT (Serotonin) 11.538 %.

TT in rs2129785, a typical for most humans. The implications of this is that this individual does not have long form 5-HTTLPR and does not have a decrease in the risk of depression.

CT in rs6311 of HTR2A, slightly increased risk of suicidal behavior and depression. Normal risk of sexual dysfunction when taking SSRI Antidepressants.

AG in rs6313 of HTR2A, Typical odds for suicidal ideation

GG in HTR2A's rs2070040, G allele is associated with lower resistance to stress, irritability, and agressive behavior.

GT in HTR2A's rs4142900, G allele is associated with higher antisocial behavior and impulsivity

AA in rs1545843, associated with higher risk for major depression, but only in individuals less than 55 years old

AA in rs17144465, typical (lower) depression risk.

GG in ESRRG's rs2377360, higher odds of depression

TT in rs364477, reduced odds of unipolar depression

TT in rs9834970 of TRANK1, below average odds of Bipolar disorder and Schizophrenia

CT in DISC1 rs1411771, somewhat higher odds of bipolar disorder and schizophrenia (does not play a role in polygenic risk scores)

Homozygous minor allele at ADCY2 gene. Associated with bipolar disorder

GG in ADCY2's rs17826816, significant increase in the odds of bipolar disorder.

CC in rs267606861, common in clinvar, no tourette

AG in rs11074889, slightly higher odds of ADHD - risk allele is A

Results Mental Health - Autism Only

Higher Odds of Autism 45.714 %.

Intermediate Odds of Autism37.143 %.

Lower Odds of Autism17.143 %.

TT in rs4307059, 1.42x risk of Autism, worse cell adhesion in neurons.

TT in rs10513025, typical , normal (higher) risk of autism.

AT in rs7794745, slightly increased risk for autism. Risk allele is T.

CC in rs1804197, common genotype. Normal (lower) risk of autism.

AA in rs2217262, typical genotype. Average (higher) risk of autism.

DDC (Dopa Decarboxylase) Gene Panel - Dopamine & Serotonin Synthesis

GG in rs930707, typical (higher) Indoleacetate levels. Indoleacetate is a tryptophan derivative and lower levels of indoleacetate are linked with depressive symptoms.

TC, or heterozygous in rs1451371,average tendency to smoke heavily if is a smoker.

Results For Lactose Persistence

GG in MCM6's rs4988235 variation, which means this individual does not carry the European lactose persistence mutation.

CC in MCM6's rs182549, This Individual does not have any derived variants for European lactose persistence.

AA in rs41380347, NOT carrier of the lactase persistence allele also known as "-13915*G", common in Arab populations

Higher Odds of Lactose Intolerance: 44.828 %.

Intermediate Odds of Lactose Intolerance: 51.724 %.

Lower Odds of Lactose Intolerance: 3.448 %.

Results for OXTR - The Empathy Gene

Lower Empathy 25.000 %.

Average Empathy 40.000 %.

Higher Empathy 35.000 %.

GG in OXTR's rs53576 variation, which means this individual has 2 variants for higher levels of empathy at this variation.

TG in rs237885, one 'sociopath' variant and one 'empath' variant in OXTR.

TC in rs1042778 of OXTR, one 'sociopath' and one 'empath' allele, the empath allele is G

GG in OXTR's rs7632287 variation, which means this individual has 2 variants for lower levels of empathy at this variation.

GG in OXTR's rs237897, two variants for higher levels of empathy in this OXTR variation. Most likely not East Asian.

Results for Diabetes

TT in rs7202877, slight decrease in risk of Type 1 Diabetes.

TG in rs12255372, 1.3x increased type-2 diabetes risk

AA in rs17696736, slighly lower odds of type 1 Diabetes

AG in rs2476601 variation, which leads to slightly high risk of various autoimmune disorders and type 1 diabetes.

GG in rs17388568, normal (lower) odds of Type 1 Diabetes.

CC in rs9273363, which leads to a 7 fold decrease in the risk of type 1 diabetes.

CG in rs7754840, which means this individual has one variant for higher odds of type 2 diabetes.

CC in rs7903146, a associated with lower risk of type 2 diabetes.

TG in rs4402960, leading to slight increase in the risk of Type 2 Diabetes.

Results for Hemochromatosis

GG in HFE's Cys282Tyr variation, which means this individual is not a carrier for the C282Y hemochromatosis mutation.

CG in HFE's His63Asp, which means this individual has one copy of the H63D variant but most likely doesn't have hemochromatosis unless also has C282Y variant.

AA in HFE's S65C variation, which means that this individual does not carry any risk variants for hemochromatosis.

Results for Alzheimers

CC in rs7412, which means no APOE2 alleles in Arg176Cys variation of the APOE gene and lower, or in other terms, normal odds of alzheimers disease.

TT in rs429358, no risk alleles for Alzheimers in this APOE variation.

GG in PLD3's rs145999145 variation, which means this individual has a lower risk of Alzheimers.

TC, or heterozygous in rs669, which leads to slightly increased risk of Alzheimers.

AG in TOMM40's rs2075650, higher odds of Alzheimer's disease.

CC in rs75932628, normal (Slightly lower) risk of Alzheimer's disease

CC in rs63750847, no variants for reduced risk of Alzheimer's disease. Normal (Higher) odds of Alzheimers

Multiple sclerosis

(Linked) likely no HLA-DRB1*1501 alleles, typical , normal (lower) risk for MS. Lower (typical) odds for narcolepsy as well.

no HLA-DRB1*1501 alleles, typical , normal (lower) risk for MS.

0 risk variants for MS in HLA-DRB1. Typical

AG in rs4959039, 1 (common) risk variant for MS.

Cardio-Vascular Disease Panel

AG in rs662799, 1.4x higher early heart attack risk; less weight gain on high fat diets

TG in rs602633, 1 risk variant for Coronary Heart Disease (Odds ratio = 1.11 for every T allele). common genotype.

GG in rs10958409, normal (lower) risk of brain aneurysm, risk allele is A

TT in rs1333040, higher odds of brain aneurysm and heart attack.

TT in rs6475606, increased risk for Coronary artery disease.

TC in rs10757272, 1.30x increased risk for Coronary artery disease, risk allele is T.

CC in rs9315204, lower risk of aneurysm, common genotype.

AG in rs10757274, 1.2x increased risk for heart disease. Risk allele is G.

GG in rs2383206, 1.7x increased risk for heart disease.

AG in rs10757278, 1.3x risk for Heart Attack. Normal risk for Abdominal Aortic Aneurysm and Brain Aneurysm.

CC in rs1800787, not a carrier of risk variants for carotid arthery disease (T).

AA in rs5082, Higher (normal) risk of heart disease.

AA in rs17576, Higher odds of heart attack, lower odds of lung cancer.

Asthma + Epilepsy Panel

CT in rs7216389, Normal risk for Childhood Asthma. Risk varian is T

GG in rs1695, 3.5x asthma risk in certain populations

CT in rs10030601, ~1.3x higher odds of epilepsy if European

CC in rs10496964, typical (higher) odds of epilepsy

AC in rs7587026, increased odds of epilepsy

AA in rs12059546, lower (typical) odds of epilepsy

AG in rs72823592, higher than average odds of epilepsy

Myopia Panel (Ordered from highest to lowest impact)

AA in rs12193446, which is the typical and leads to slightly increased risk of myopia, or nearsightedness.

AC in rs7744813, which leads to a slight increase in the risk of myopia.

TT in rs524952, which means an increased risk of myopia.

AC in rs4803455, one allele that protects from Myopia.

CG in RBFOX1's rs17648524, one allele that protects against myopia.

CT in rs3138142, one allele that protects against myopia.

Facial Morphology Panel

AA genotype in EDAR's rs3827760, Likely no shovel shaped incissors and not East Asian in ancestry

AA in rs6542787, 2 European EDAR alleles. Likely a European with European facial morphology

AA genotype in EDAR's rs260690, European facial traits. Very uncommon genotype for East Asians. Typical for Europeans.

CC in rs892540, longer (typical) midface length

AA in PAX3s rs7559271, higher odds of protruding nasal bridge

Likely higher nasolabial angle (nose pointing up) based on DCHS2 genotype

CC in rs938036, likely has mandibular third molar, lower odds of tooth agenesis (missing teeth)

TT in rs12651896, slightly thinner eyebrows

AG in rs7702108, intermediate eyebrow thickness

Miscellaneous

(Don't voice this in video!!) CC in rs9332964, no micropenis.

(Don't voice this in video!!!) GG in SRD5A2's rs104893667 variation, which means this individual does not have micropenis.

TT in rs10784502, smaller cranium and lower IQ.

TT in rs28379706, lower IQ.

AG in rs324640, 4 points higher IQ than individuals with 'AA' .

CT in rs1815739, Mix of muscle types. Likely more sprinter than endurance athlete.

AT , 1 'fat gene' variant in FTO's rs9939609. Higher odds of obesity and sleep apnea.

CC in rs10427255, likely has photic sneeze reflex.

GG in SCN9A rs6746030 variation, no variants for increased pain sensitivity.

AA genotype in EDAR's rs3827760, Likely no shovel shaped incissors and not East Asian in ancestry

AA genotype in EDAR's rs260690, European facial traits. Very uncommon genotype for East Asians. Typical for Europeans.

GG in rs671 variation, Not an Asian flusher, lower odds of Alcoholism. Normal risk of Esophageal Cancer.

CC in rs6265, higher odds of obesity and major depressive disorder

Drug Responce

Risk of Heart Failure Due to Beta Blocker Medications is 1.000 times the average.

When treated with metoprolol

Relative to AA in rs1801252 & GG in rs1801253 Genotypes :

rs1801252(A;A) and rs1801253(C;C) carriers: 15 point drop in Blood Pressure
rs1801252(A;G) and rs1801253(C;C) carriers: 9 point drop in Blood Pressure
rs1801252(A;A) and rs1801253(C;G) carriers: 6 point drop in Blood Pressure
rs1801252(A;G) and rs1801253(C;G) carriers: 1 point drop in Blood Pressure

Your genotypes are : &

AA in CYP2C9's rs1057910, normal; no effect on warfarin metabolism

GG in rs3745274, no increased risk when taking efavirenz for HIV treatment

AA in rs28399433, No Reduced CYP2A6 metabolism and no impaired nicotine metabolism - typical genotype

AA in rs1801272, no reduced CYP2A6 metabolism, no impaired nicotine metabolism, typical genotype

CT in CYP1A2's rs12720461, carrier of one CYP1A2*1K_-729C>T allele, decreased CYP1A2 activity

GG in rs4986893, no CYP2C19*3 allele (Good)

TT in rs4363657, lower(typical) myopathy risk for statin users

AG in rs637644, average odds of hair loss from chemotherapy- risk allele is G.

AG in rs594206, 1 allele for lower odds of hair loss from chemotherapy (G).

GG in DRD1's rs265976, Patients with schizophrenia may have a better response when treated with clozapine as compared to patients with the GT genotype. Other genetic and clinical factors may also influence response to clozapine.

GG in rs2273697, Adverse reaction less likely to carbamazepine in epileptic patients

AC in rs762551, Carrier of one CYP1A2*1F allele; Normal (faster) metabolism of caffeine

CC in rs3892097, extensive CYP2D6 metabolizer

CC in rs1467558, lower (normal) risk of liver toxicity from acetominophen/tylenol/APAP

CC in rs10156191 of AOC1, normal (increased) DOA activity, normal genotype. Tolerates NSAIDs.

TC, or heterozygous in rs4765623, more likely to gain weight if taking olanzapine.

CC in rs3813929, higher odds of weight gain if taking olanzapine.

GG in rs518147, significantly higher odds of weight gain if taking olanzapine.

TT in AKT1's rs2494732, lower odds of Cannabis induced psychosis.

GG in rs2241802, higher odds of methamphatamine induced psychosis.

CG in rs135745, slightly higher susceptibility to methamphetamine induced psychosis.

AA in rs12591257, no protection from Methamphetamine induced psychosis

Albinism & Atypical Traits Panel

CC in OCA2's rs121918166, Not Carrier of an oculocutaneous Albinism Type II mutation.

AA in TYR's rs28940881 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.

AA in TYR's rs28940878 variation, which means this individual does not have any Tyrosinase-negative oculocutaneous albinism mutations.

TT in rs61754381, which means not a carrier for 1B Tyrosinase-negative oculocutaneous albinism.

CC in TYR's rs104894313, Not Carrier of an oculocutaneous Albinism Type 1B mutation.

CC in TYRP1's rs104894130, which means this individual lacks variants for Oculocutaneous albinism type 3, and is not albino.

AC in rs987525, which leads to 2.5x increased risk for cleft lip.

CC in TYRP1's rs387907171, not a Carrier of melanesian blond hair variants.

Familiar Mediterranean Fever Panel

0 risk variants in rs3743930.

0 risk variants in rs28940579.

0 risk variants in rs28940578.

0 risk variants in rs61732874.

0 risk variants in rs104895097.

0 risk variants in rs104895085

0 risk variants in rs104895081

0 risk variants in rs104895157

0 risk variants in rs11466024

0 risk variants in rs79681911

MTHFR panel

GG in MTHFR's rs1801133, normal homocysteine levels, good . Slightly lower than average odds for a variety of illnesses from autism to coronary heart disease.

TG in MTHFR's rs1801131, Possibly impaired folate metabolism.

GG in rs17367504, very uncommon , lower blood pressure.

CC in rs2274976, Good, lower odds of neural tube defects

AA in rs2066470, higher odds of Neural tube defects.

Cancers Panel

Prostate

AG in rs4430796, average odds of prostate cancer - risk allele is A.

GG in rs1859962, higher odds of prostate cancer.

CC in HOXB13's rs138213197, normal (lower) risk of prostate cancer in men

No rare variant for prostate cancer

GG in 8q24 rs6983267, 1.6x increased risk for prostate cancer; also other cancers

AC in 8q24 rs1447295, 1.4x increased risk for prostate cancer

Breast - BRCA

0 risk variants in BRCA1's D693N.

0 risk variants in S1140G of BRCA1

1 risk variant in K1183R of BRCA1

TT in rs1801155, average (lower) risk of colon cancer

0 risk variants in S707P

AG in Estrogen Receptor 1 Gene's -351A>G variation. Women have normal (lower) risk of Endometriosis, 0.75x lower risk of Endometrial Cancer, and normal (higher) risk of cognitive impairment.

Testicular - KITLG

GG in rs995030, common , slightly higher risk of testicular cancer.

TT in rs3782179; common, but increased risk of testicular cancer

AA in rs4474514, >3x increased testicular cancer risk for men

Leukemia Panel

GG in rs1800566, 0 NQO1*2 alleles (0 risk variants for leukemia)

GT in rs4132601, somewhat (1.7x) increased risk for acute lymphoblastic leukemia.

TT in rs7089424, common/normal and lower risk of Leukemia.

AG in rs2239633, average odds of leukemia.

AG in rs662463, slightly higher odds of leukemia, uncommon genotype.

Rare diseases/traits Panel

No rare variant for prostate cancer

AA in F9 rs137852229, not a Carrier of a Hemophilia B mutation - 0 risk variants

Some predisposition to hemoglobin E disease, GT in rs2071348

CC in rs119478057, no predidposition to Hypercarotenemia and vitamin a deficiency

GG in rs387906725, no Lesch-nyhan syndrome.

GG in rs28942100, not a Carrier of a alkaptonuria mutation - 0 risk variants

TT in rs121434622, no Fragile X syndrome

CC in rs199473058, no Brugada Syndrome

GG in rs121434528, 0 risk alleles for Thoracic aortic aneurysm and dissection

GG in rs74315329, not a carrier for Glaucoma (primary open-angle).

AA in rs893818, ~10x higher odds of Exfoliation glaucoma.

CC in rs28936694, no Primary open-angle glaucoma

AG in rs16863657, carrier of risk allele for neural tube defects and spina bifida.

GG in rs80338794, not a Finnish major Salla disease mutation carrier - 0 risk variants.

0 variants for Ehlers-Danlos syndrome; CC in rs28937869

Found 0 risk variants for Holoprosencephaly in GLI2. Very typical/common genotype

Typical genotype, no Holoprosencephaly-3 risk variants in SSH

GG in rs34536443, typical (lower) odds of tuberculosis infection, common genotype

TG in rs10033464, 1.28x increased risk of Atrial Fibrillation and cardioembolic stroke.

AA in rs660895, decreased risk of rheumatoid arthritis. Slightly decreased risk of IgA nephropathy - a disease in which IgA protein builds up in and damages the filtering part of the kidney (glomerulus)

AA in rs7743761, 20x increased risk of Ankylosing Spondylitis.

CC in rs6457617, normal (lower) risk for RA and Systemic sclerosis

GG in rs11090865, common in clinvar, no risk variants for deafness.

GG in rs13078881, Healthy - no Biotinidase deficiency.

CT in rs6151429, carrier of one pseudoarylsulfatase A deficiency allele (C)

TT in rs4794067; Lower risk of Aspirin Induced Asthma. Normal (higher) risk of lupus and intractable Grave's Disease.

CC in rs10156191 of AOC1, normal (increased) DOA activity, normal genotype. Tolerates NSAIDs.

GG in rs104894637 - not a carrier for Sanfilippo syndrome risk

CC in rs104894635, no risk variants for Sanfilippo syndrome

No von Gierke's disease. CC in Arg83Cys of glucose-6-phosphatase G6PC gene.

GG in Cys1036Phe of BLM, not a carrier of variants for Bloom syndrome.

AT, or heterozygous in rs12150220, slightly increased risk for several autoimmune diseases including Addison's disease.

CC in rs1800546, normal.

TT in rs74315405, no Gerstmann–Straussler–Scheinker syndrome.

GG in rs11606250, most common , but higher risk for certain autoimmune diseases.

AA, 0 risk variants in rs2302009.

Celiac Disease Panel

average, no HLA-DRB1*0301 alleles, normal risk of celiac disease and lupus.

no HLA-DQ8 haplotype, normal (lower) risk of Celiac disease.

1 risk variant in CCR3

1 risk variant in IL18R1

AA in rs13119723, lower (normal) risk for celiac disease. 0 risk variants

No risk variants in R262W

Allergies Panel

AG in rs2367563, slighly higher odds of allergic skin reaction to nickel - risk variant is A.

TG in rs2155219, 1 allele for higher odds of allergies. Odds Ratio for every T allele = 1.18

CC in rs17513503, lower odds of allergies; common

TT in rs7192, 3x higher risk for developing a peanut allergy.

CC in rs9275596, 3x (relative to TT ) increased risk for developing a peanut allergy.

Androgen Receptor Gene (AR) Panel

CC in rs137852591, very typical ; no Androgen insensitivity.

GG in rs9332969, normal , no Reifenstein syndrome.

GG in rs9332971, normal , no Reifenstein syndrome.

Crohn's Disease Panel

GG in rs2066845, normal (lower) risk for Crohn's disease. Risk allele is C.

Canavan Syndrome Panel

0 risk variants in A305E.

0 risk variants in E285A.

If you have more than 0 risk variants for Canavan syndrome, that is cause for concern. May be the result of genotyping errors depending on the chip you tested with.

HIV & AIDS Panel

HIV does not develop and transition into AIDs the same way with every organism. Some are predisposed to larger viral load and quicker compromisation of the immune system while others are more resistant.

0 protective variants in C927T (Bad), most typical genotype.

1 protective variant in HLA-C's rs9264942 (Good), atypical genotype. 60% reduction in HIV viral load

common (Good), no risk variants in rs2395029 (TT )

GG in rs2572886, Good , 0 risk variants (A), common.

HLA Gene Panel

The HLA genes are located on chromosome 6 in humans and encode proteins called human leukocyte antigens (HLAs). These proteins play a vital role in immune responses by presenting antigens to immune cells, specifically T cells. There are two main classes of HLA proteins: class I and class II.

The HLA system plays a critical role in several medical contexts, including organ transplantation, where matching HLA types between donor and recipient is crucial to minimize the risk of rejection. Additionally, HLA genes are associated with susceptibility to certain autoimmune diseases, infectious diseases, and drug hypersensitivity reactions, making them important targets for medical research and personalized medicine.

Here is a list of conditions affected by, and predicted by this Panel: Rheumatoid arthritis, systemic lupus erythematosus (SLE), type 1 diabetes mellitus, multiple sclerosis (MS), Sjögren's syndrome, inflammatory bowel disease (IBD) – Crohn's disease and ulcerative colitis, celiac disease, ankylosing spondylitis, systemic sclerosis, psoriasis, Graves' disease, Hashimoto's thyroiditis, Addison's disease, vitiligo, myasthenia gravis, primary biliary cholangitis, autoimmune hepatitis
Susceptibility or severity of certain viral infections (e.g., HIV, hepatitis B and C), some bacterial infections (e.g., leprosy, tuberculosis)
Food allergies (e.g., peanut allergy, milk allergy), Allergic rhinitis (hay fever), Atopic dermatitis (eczema), Asthma
Allograft rejection, Preeclampsia, and Certain neurological disorders (e.g., narcolepsy)

Highest odds of Autoimmune Disease 16.667 %

Intermediate (Slightly higher) Odds of Autoimmune Disease 40.000 %

Lower Odds of Autoimmune Disease 43.333 %.

MTRR Gene Panel

AG in rs1801394, slightly higher odds for meningomas and neural tube defects. 1 risk allele for disorders of Intracellular Cobalamin Metabolism

CC in rs10380, lower odds of pancratic cancer; 0 risk alleles for disorders of Intracellular Cobalamin Metabolism

AA in rs162036, no risk variants for spina bifida & Disorders of Intracellular Cobalamin Metabolism.

CC in rs2287780, no risk variants for Disorders of Intracellular Cobalamin Metabolism

TT in rs2303080, 0 risk alleles for disorders of Intracellular Cobalamin Metabolism

AG in rs1802059, 1 risk allele for disorders of Intracellular Cobalamin Metabolism

CBS Panel

CT in CBS's rs234714, intermediate Plasma homocysteine levels (highest impact snp)

CT in CBS's rs234709, slightly decreased homocysteine levels

Predisposed to intermediate levels of Plasma homocysteine, CT in rs2851391, T allele leads to lower levels

homocystinuria Panel

We found Risk variants in : rs1789953(1) and a total of 1 risk variants for homocystinuria in CBS gene out of 16 variants identified in your file in total.

Elevated homocysteine levels 16.667 %

Intermediate homocysteine levels 54.167 %

Lower homocysteine levels 29.167 %.

Thyroid Cancer Panel

GG in rs1867277, slightly lower odds of thyroid cancer.

GG in rs965513, normal(lower thyroid cancer risk).

CC in rs944289, lower thyroid cancer risk

CC in rs116909374, typical(lower) odds of thyroid cancer

TT in rs966423, lower odds of thyroid cancer

Muscular Dystrophy Myopathies

0 risk variants in rs121913574

0 risk variants for Duchenne muscular dystrophy in rs1800278

0 risk variants in rs28937903

0 risk variants in rs28937904

0 risk variants in rs28928901

0 risk alleles in rs2296949

0 risk alleles in rs104894466

0 risk variants in rs28937900

0 risk variants in rs193922094

Found : 0 risk variants for adrenoleukodystrophy out of 30 Total

If you have risk variants here, it is most likely caused by miscalls in your raw data.

Since ADL is an X-linked condition, males can not be carriers. If you are male over the age of 20 and see risk variants here, it is due to miscalls. Otherwise you would be dead.

Colorblindness Panel

0 risk variants in OPN1LW out of 2

0 risk variants in OPN1MW out of 0

0 risk variants in OPN1SW out of 8

FTO Gene Panel

Higher Odds of Obesity 13.889 %.

Intermediate Odds of Obesity47.222 %.

Lower Odds of Obesity38.889 %.

No risk variants for obesity in rs9930506, lower risk of obesity

No fat gene variants in rs1421085, lower odds of obesity

GG in rs9937053, lower BMI

No fat gene variants in rs11642015, lower odds of obesity

AG in rs1121980, slightly higher BMI. Slight increase (1.67x) in risk for obesity

AT , 1 'fat gene' variant in FTO's rs9939609. Higher odds of obesity and sleep apnea.

AA in rs9928094, lower odds of extreme obesity

Within PFKP Gene - also implicated in Obesity

GG in rs6602024, lower BMI

Others also implicated in Obesity

AG in rs4994, higher odds of obesity. Risk allele is G. Kind of an uncommon genotype.

TT in rs6232, lower risk of obesity and insulin sensitivity

Syncope Panel

A syncope, commonly known as fainting, is a temporary loss of consciousness and muscle tone caused by a brief reduction in blood flow to the brain. This sudden and temporary loss of consciousness typically results from a drop in blood pressure, leading to a momentary interruption of oxygen and nutrient supply to the brain. Syncope episodes are often brief, lasting only a few seconds to a couple of minutes, and individuals usually recover spontaneously once blood flow is restored. Various factors, such as dehydration, low blood sugar, or sudden changes in body position, can contribute to the occurrence of syncope.

AC in rs12465214 of ZNF804A, slightly decreased odds of Syncope (good allele is A). Odds ratio of ~0.98, this is the lowest pval (most statistically significant) snp for syncope risk

AG in rs1431318, average odds of syncope. The risk allele is A

Used 4 snps in the following prediction

Syncope risk is 0.980 times the average

Bio Traits Panel

AA in MTR's rs1805087, decreased MTR activity and increased homocysteine levels (doesn't contribute to homocysteine panel score)

CT in rs174547, one allele for lower resting heart rate (C), one allele for lower omega-6 & omega-3 levels (C), common genotype

ACE I/D genotype, increased ACE activity - healthier, reduced odds of hypertension and a range of other issues.

CT in rs1544410, Intermediate risk of low bone mineral density disorders

AG in rs1051730, 1.3x increased risk of lung cancer - indirect contribution to risk of lung cancer through an increase in the risk of nicotine dependence

rs5443 (TT) are clearly at higher risk for hypertension, 2-3 fold more likely to be obese, rs5443(T;T) genotypes respond to Viagra better. rs5443(T;T) patients receiving clozapine over a long term for the treatment of schizophrenia gain significantly more weight (16%) compared to patients carrying at least one rs5443(C) allele in a study of Chinese patients. rs5443(T) carriers taking triptans for the treatment of migraines or cluster headaches were ~3 fold more likely to respond positively compared with rs5443(C;C) homozygotes (OR 2.96, CI:1.34 - 6.56, p=0.0074) in a study of ~200 Caucasian patients.

TT in rs185819, ~30mm shorter

TT in rs1042725, ~0.8cm shorter height relative to CC genotype

TT in rs6060369, ~0.88cm shorter height relative to CC genotype

AA in rs10946808, taller.

GG in rs1800795, more IL6, significantly associated with type-2 diabetes (odds ratio 1.51)

AA in rs1380703, longer (typical) sleep duration

CC in rs2148710, lower predisposition to anger

Wet earwax. Normal (smellier) body odour. Normal colostrum. Typical for non-East Asians. CC in rs17822931

One copy of "hunter-gather" CLTCL1 gene variant + one "farmer" variant. Intermediate ability to process carbs and sugars. Farmer allele is C

AG in rs662799, 1.4x higher early heart attack risk; less weight gain on high fat diets

CT in rs27072, Lower risk of alcohol withdrawal seizures, and perhaps lower odds of ADHD.

GG in rs4481887, least likely to be able to smell asparagus metabolites in urine

AA in rs6591536, less able to detect β-ionone (floral) fragrance

GG in rs11800854, higher (typical) odds of periodontitis

AG in rs234706, 0.94 reduced risk of cleft lip / palate

Age Related Macular Degeneration

CC in rs1061147, Reduced 0.34x risk of Age Related Macular Degeneration.

TT in rs1061170; lower risk for AMD, generally longer live than (C) allele carriers

GG in rs2230199, normal (reduced) risk for AMD

CC in rs380390, much higher odds of AMD

CC in rs3793917, lower (typical) odds for AMD

GG in rs800292, 2x increased odds of Age-related macular degeneration (MTAG)

Cataracts Panel

CC in rs8044853, ~1.3x higher odds of cataracts

AG in rs1929494, ~1.1x risk for cataracts

CC in rs926937, higher(typical) risk of cataract

Vitamins and Levels

TT in rs2282679 of GC gene, normal levels of Vitamin D.

GG in rs12785878, higher levels of Vitamin D.

GG in rs10741657, tend to have lower vitamin D levels

CT in rs6544713, slightly higher LDL cholesterol

GG in rs6756629, associated with increased LDL levels, decreased HDL cholesterol levels, and increased triglyceride levels.

CT in rs560887, slightly decreased blood sugar (T allele decreases blood sugar)

TT in rs10047474, increased blood pressure

GG in rs4961, lower blood pressure

AA in rs4895441, lower red blood cell count

CT in rs140522, intermediate red blood cell count. T allele increases red blood cell count

CC in rs1063739, protection of neurons against glutamate toxicity, increased (normal) rate of glutamate degradation

AG in rs602662, average (intermediate) vitamin B12 Levels. A allele leads to Higher B12 levels. 49.77 pg/ml increase per A allele relative to GG genotype

CC in rs34324219, higher (Typical) vitamin B12 levels.

CC in rs4654748, 1.45 ng/ml decrease in B6 levels

Predisposed to intermediate levels of Vitamin A/Retinol, CT in rs780093, T allele leads to higher levels

GG in rs11057830, lower(typical) levels of Vitamin E.

GG in rs6862909, typical genotype, higher - typical Vitamin K levels

CG in rs964184, higher levels of vitamin K.

CC in ARSD's rs1637781, higher Ascorbic acid 3-sulfate levels

DVT Panel

CT in rs11121615, average odds of varicose veins. The 'good' allele is T. Highest pval and beta snp for this trait

CC in rs6025, lower (normal) risk of deep vein thrombosis

GG in rs1799963, lower risk of deep vein thrombosis

AG in rs7025486, slight (1.2x) increase in risk for abdominal aortic aneurysm and some vascular disorders, risk allele is A

Blood Group Panel

CC in rs9919007, likely blood type A or O. 0.74 accuracy

CC in rs635634, higher odds for all blood types besides A. 0.92 accuracy

TT in rs8176720, likely A or O blood type. 0.77 accuracy

GG in rs7030248, Likely no Blood type B or AB. Accuracy 0.74

TT in rs493014, no blood type B or AB. Accuracy 0.75.

GG in rs8176746, likely not blood type AB. Accuracy 0.75.

AA in rs8176740, slightly lower odds of B and O blood types

GG in rs1053878, 0 alleles for cis-AB blood type, cis-AB blood type less likely.

Blood Type Likelyhood Distribution

Type O: 53.373 %

Type A: 46.241 %

Type B: 0.322 %

Type AB: 0.064 %